In the Godfather (b00k), Don Corleone always wants to know whether his target is a “Sicilian.”
What he means is: Is he unafraid of losing everything?
The Don knows there is not much he can do against a fearless opponent.
But once he’s found what the opposition fears losing, he can exploit it to get what he wants.
Make sure you overcome your fears of losing money/face/friends/whatever.
Otherwise the opposition will take advantage and beat you.